David Irby
Laboratory Manager
Department of Surgery
Personal Statement
With 35 years of experience working in medical research laboratory science, I have a broad understanding of experimental design, data analysis, quality control, and safety awareness. My acquired abilities, personality, and organizational skills allow me to collaborate effectively with diverse teams of physician scientists, researchers, and administrators, which is critical to ensure optimal, efficient project execution and facilitate research findings into medical applications, all of which result in a medical research laboratory that is consistently a “cut above” other research intensive institutions, as we are goal-oriented, knowing that we are limited only by our own desire and determination to succeed.
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After 35 years of scientific research, I live by the following quote,
“No Matter How Long You Live, Never Grow Old. Never cease to stand like curious children before the great mystery into which we were born.”- Albert Einstein
Selected Articles
1. Krinock DJ, Stephenson K., Irby DJ, Akmyradov C, Barker M, Waldrip Z., Burdine M, Wolf LL, Dassinger MS and Wyrick D. Intra-peritoneal povidone-iodine irrigation decreases abscesses in a perforated appendicitis murine model. Journal of Pediatric Surgery 2025;60(3), 162081.
2. Goode GA, Wagh SJ, Irby DJ, Ma D, Jacobs RF, Kearns GL, Almoazen H. Bioavailability testing of a newly developed clindamycin oral suspension in a pediatric porcine model. ​Development & Technology 2019. 24(8):1038-1043.
3. Ronis MJ, Hakkak R, Irby DJ, Shelnutt SR, King S, Cimino C, Badger TM. Development of a rat total enteral nutrition model for delivery of high levels of dietary phytoestrogens using soy protein isolate. Journal of Medicinal Food 2009. 2(3-4):223-5, 2009.
4. Perrien DS, Brown EC, Fletcher TW, Irby DJ, Aronson J, Gao GG, Skinner RA, Hogue WR, Feige U, Suva LJ, Ronis MJ, Badger TM, Lumpkin CK Jr. Interleukin-1 and tumor necrosis factor antagonists attenuate ethanol-induced inhibition of bone formation in a rat model of distraction osteogenesis.
Journal of Pharmacology & Experimental Therapeutics 2022. 303(3):904-8.
5. Brown EC, Perrien DS, Fletcher TW, Irby DJ, Aronson J, Gao GG, Hogue WJ, Skinner RA, Suva LJ, Ronis MJ, Hakkak R, Badger TM, Lumpkin CK Jr. Skeletal toxicity associated with chronic ethanol exposure in a rat model using total enteral nutrition. Journal of Pharmacology & Experimental Therapeutics 2002. 301(3):1132-8.
6. T M Badger, Crouch J, Irby DJ, Hakkak R and Shahare M. Episodic excretion of ethanol during chronic intragastric ethanol infusion in the male rat: continuous vs. cyclic ethanol and nutrient infusions. Journal of Pharmacology and Experimental Therapeutics 1993. 264 (2) 938-943.
7. Ronis MJ, Huang J, Crouch J, Mercado C, Irby DJ, Valentine CR, Lumpkin CK, Ingelman-Sundberg, M.A.G.N.U.S. and Badger TM. Cytochrome P450 CYP2E1 induction during chronic alcohol exposure occurs by a two-step mechanism associated with blood alcohol concentrations in rats. Journal of Pharmacology and Experimental Therapeutics 1993. 264(2), 944-950.
8. Badger TM, Ronis MJ, Lumpkin CK, Valentine CR, Shahare M, Irby DJ, Huang J, Mercado C, Thomas P, Ingelman-Sundberg M. Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat. The Journal of Pharmacology and Experimental Therapeutics 1992, 264(1):438-447.